Effect Of Ethanol Extract Of Gouania Longipetala On Selected Clinically- Important Enzymes Of Acetaminophen-Overdosed Albino Rats:- Ukoha, Goodness C.

GOODNESS CHISOM | 43 pages (7662 words) | Projects
Biochemistry | Co Authors: UKOHA

ABSTRACT

The albino rats were randomly divided into five groups each consisting offour albino rats Group 1 rats were the normal control and were given feed and water adlibitum for a period of 14 days. Hepatotoxicity was induced invivo in all the rats ofGroups 2’ n 4 5 orally by administermg 1 -5g /kg body weight ofparacetamol. Group 3, 4 and 5 were orally administered Gouania longipetela 200 mg/kg, 600mg/kg and lOOOmg/kg body weight respectively daily for a period of 14 days. Group 2 rats were the negative control and they were not given the extract. The result of this study shows that rats treated with Gouania longipetela extract significantly (P<0.05) have reduced clinically important liver enzymes Oral administratmn ofacetaminophen caused marked liver damage as noted by the significant increased (P<0.05) m activities ofplasma AST, ALT and ALP. Treatment with the extract showed effective hepatoprotection as evidence in the decrease in the plasma levels ofliver biomarker enzymes.

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APA

GOODNESS, C (2024). Effect Of Ethanol Extract Of Gouania Longipetala On Selected Clinically- Important Enzymes Of Acetaminophen-Overdosed Albino Rats:- Ukoha, Goodness C. . Repository.mouau.edu.ng: Retrieved Apr 25, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-ethanol-extract-of-gouania-longipetala-on-selected-clinically-important-enzymes-of-acetaminophen-overdosed-albino-rats-ukoha-goodness-c-7-2

MLA 8th

CHISOM, GOODNESS. "Effect Of Ethanol Extract Of Gouania Longipetala On Selected Clinically- Important Enzymes Of Acetaminophen-Overdosed Albino Rats:- Ukoha, Goodness C. " Repository.mouau.edu.ng. Repository.mouau.edu.ng, 26 Feb. 2024, https://repository.mouau.edu.ng/work/view/effect-of-ethanol-extract-of-gouania-longipetala-on-selected-clinically-important-enzymes-of-acetaminophen-overdosed-albino-rats-ukoha-goodness-c-7-2. Accessed 25 Apr. 2024.

MLA7

CHISOM, GOODNESS. "Effect Of Ethanol Extract Of Gouania Longipetala On Selected Clinically- Important Enzymes Of Acetaminophen-Overdosed Albino Rats:- Ukoha, Goodness C. ". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 26 Feb. 2024. Web. 25 Apr. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-ethanol-extract-of-gouania-longipetala-on-selected-clinically-important-enzymes-of-acetaminophen-overdosed-albino-rats-ukoha-goodness-c-7-2 >.

Chicago

CHISOM, GOODNESS. "Effect Of Ethanol Extract Of Gouania Longipetala On Selected Clinically- Important Enzymes Of Acetaminophen-Overdosed Albino Rats:- Ukoha, Goodness C. " Repository.mouau.edu.ng (2024). Accessed 25 Apr. 2024. https://repository.mouau.edu.ng/work/view/effect-of-ethanol-extract-of-gouania-longipetala-on-selected-clinically-important-enzymes-of-acetaminophen-overdosed-albino-rats-ukoha-goodness-c-7-2

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