Effect Of Ethanolic Leaf Extract Of Telfairia Occidentalis And Tectona Grands On Levels Of Cd4 Count Total White Blood Cell (TWBC And Packed Cell Volume (PCV) On Mice.

ABSTRACT

Immune system is a system of biological structures and processes within an organism that protects against disease. The integral i-ole of this system can be accounted for by its tendency to detect a wide variety of agents. from viruses to parasite worms. and distinguish them from the organisms own healthy tissue. Pathogens can rapidly evolve and adapt to avoid detection and neutralization by the immune system . as a result, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen. leading to an enhanced responses to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination. Immunodeficiency occurs when the immune system is less active than normal . resulting in recurring and life threatening infections. Telfairia occidentalis and Tectona grandis plays important role in human and livestock nutrition s. The poor state of economy in developing countries has made consumption of high protein food out of reach of more than 65-70% (Nworgu. 2004). One of the ways of solving this problem is to use unconventional sources of protein and leaf protein to supplement the diet of man farm animals. The herbal preparation of the plant has been employed in the treatment of sudden attack of convulsion, malaria and anaemia (Adedapo et al 2002). The leaves of Telfairia occcidentalis and Tectona grandis are medicinally useful They possesses anti-inflammatory anti bacterial, anti fungal. antidiuretic as well as erythropoietic properties.