Comparative Analysis Of The Antibacterial Potential Of Some Brands Of Toothpaste Commonly Used In Umuahia:- Ihesiulo, Stella C.

ABSTRACT

This in vitro study was carried out to determine .he antibacterial efficacy of different toothpaste against three pathogens isolated from the mouth (Escherichia coli, Staphylococcus aureus, and Streptococcus spp). A total of six (5) toothpastes were tested for their antibacterial activity by disc diffusion method. Holder.t toothpaste showed maximum zone of inhibition against Staphylococcus aureus, Escherichia coli and Streptococcus spp compared to all other toothpastes. All the concentrations of Oral B and Holdent inhibited Staphylococcus aureus. Close up herbal and Oral B produces the same result against Streptococcus spp at all the concentrations. In this research work, it has been demonstrated that Triclosan containing toothpaste formulations, such as Holdent is more effective in the control of oral micro flora compared to non-Triclosan containing toothpaste like 2080. This work therefore suggests that this toothpaste effectively reduce the total bacterial load of the mouth.