Biochemechical and Bioactive studies on Extracts of Xylopia Aethiopica and ocimum gratissimum.

ABSTRACT

 Phytochemical and bioactivity studies on extracts Fea Xylopia aethiopica and Ocimum gratissimum was carried out. Phytochemical screening reveal the presence of tannins, phytates, cyanogenic glycosides, steroids, flavonoids. Alkaloids in both plants. Quantitative analysis of the phytochemicals present showed that Xylopia aethiopica had the highest tannin content (20.95mg/100g) while the tannin conent in Ocimum gratissimum was found to be 21.41mg/100g. Xylopia aethiopica and Ocimum gratissimum had a high oligosaocharide contents (49.2% and 12.2% respectively). Alkaloid content in both plants were slightly high with Xylopia aethiopica having 1.37% and Ocimum gratissimum having 1.23%. phytate content of Xylopia aethiopica and Ocimum gratissimum was found to be 0.103mg/100g and 0.058mg/100g respectively. The extracts of both plants showed a high bioactivity with the ethanolic extract of Xylopia aethiopica having the highest bioactivity with an EDso (15.9g/ml) followed by the aqueous extract of O. grastissimum having an EDso (23.95ug/ml). The ethanolic extract of 0. gratissimum also indicated a high bioactivity (26.3g/ml), the aqueous extract of X aethiopica had an EDsp of 27.5yg/ml.