Assessment Of The In-Vitro Anti-Bacterial Activity Of Pterocapus Santalinoides And Ageratum Conyzoides:- Ajah, Stephen O

ABSTRACT

 The antibacterial and phytochemical screening of A. conyzoides and P. santalinoides were carried out to find the medicinal importance of these plants among the people of Ikwuano L.G.A in Ahia State. Agar well diffusion method was used to measure the zone of inhibition and broth dilution assay to assess the Minimum Inhibitory Concentration (MIC) of the antibacterial activity testing of the methanol extracts of these plant extracts against selected susceptible organisms. The four test bacteria used were Staphylococcus aureus (A TCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (A TCC) and Salmonella typhi. The methanol extract of A. conyzoides produced a diameter of zone of inhibition of 12.00mm against Staphylococcus aureus, 00.00mm against Pseudomonas aeruginosa, 00.00mm against Salmonella typhi while Methanol extract of P. santalinoides produced a diameter of zone of inhibition of 14.00 mm against Staphylococcus aureus, 10.00mm against Pseudomonas aeruginosa, 11.00mm against Salmonella typhi. Both plants extract had no effect on Escherichia coli. The phytochemical screening of these plants leaves showed the presence of alkaloids, tannins, Saponins, phenol and flavonoids. The research work suggests the use of A. conyzoides and P. santalinoides in herbal medicine.