Antimicrobial Activity Of Combretum Erythrophylum And Nauclea Latifolia On Some Clinical Isolates

ABSTRACT

 The comparative studies of extracts of leaves, of Combretum erythrophylum and Nauc/ea latifolia with respect to their phytochemical and antimicrobial properties was carried out. Preliminary screening for phytochemical components showed that both plants had similar constituents, namely tannins, alkaloids, saponins and phenols, but variable proportions of flavonoids. The antimicrobial screening of the water and ethanolic extracts of the various plants materials were carried out against clinical isolates of Pseudomonas aeruginosa, Klebsiella pneumonias, Escherichia coli, Staphylococcus aureus, Streptococcus pneumonia and Candida • albicans. Ethanolic extracts were more potent than aqueous extracts showing inhibition zone diameters of 9-10mm and activity were concentration dependent Staphylococcus aureus and Streptococcus pneumonia were more sensitive to the ethanolic extracts of both plants as indicated by zone diameters of 9mm and I Omm,respectively.