The Evaluation Of Hypoglycemic And Hypolipidemic Potentials Of Sweet Potato On A Wistar Albino Rat:- Okoroafor Chizaram B
ABSTRACT
The
lipidemic effect of methanol extract ofIpomoea batatas was evaluated in this
study. A total of 18 adult female wistar albino rats were purchased from the
Veterinary Department, University of Nigeria, Nsukka and acclimatized for a
period of 2 weeks with Vital growers mash feed and water administered ad
libitum. The animals were then grouped into 6 groups (n=3). Group 1 served as
control while group 2 was administered gilbenclamide. Groups 3, 4, 5 and 6 were
administered 1000 mg/kg, 750 mg/kg, 500 mg/kg and 250 mg/kg body weight of the
extract daily. The administration was done for a period of 7 days and the
animals were sacrificed, blood collected and serum collected for laboratory
analysis. The result of analysis shows a significant (p<0.05) decrease in
blood sugar level in the extract -treated groups when compared with the normal
control. The lipid profile test also show a significant (p<0.05) decrease in
VLDL and TAG in the treated group when compared with the normal control. This
work shows that I. batatas is a good antilipidemic plant and will also serve as
a good means of diabetes management.
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CHIZARAM, B (2024). The Evaluation Of Hypoglycemic And Hypolipidemic Potentials Of Sweet Potato On A Wistar Albino Rat:- Okoroafor Chizaram B. Repository.mouau.edu.ng: Retrieved Dec 21, 2024, from https://repository.mouau.edu.ng/work/view/the-evaluation-of-hypoglycemic-and-hypolipidemic-potentials-of-sweet-potato-on-a-wistar-albino-rat-okoroafor-chizaram-b-7-2
BLESSING, CHIZARAM. "The Evaluation Of Hypoglycemic And Hypolipidemic Potentials Of Sweet Potato On A Wistar Albino Rat:- Okoroafor Chizaram B" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 09 Dec. 2024, https://repository.mouau.edu.ng/work/view/the-evaluation-of-hypoglycemic-and-hypolipidemic-potentials-of-sweet-potato-on-a-wistar-albino-rat-okoroafor-chizaram-b-7-2. Accessed 21 Dec. 2024.
BLESSING, CHIZARAM. "The Evaluation Of Hypoglycemic And Hypolipidemic Potentials Of Sweet Potato On A Wistar Albino Rat:- Okoroafor Chizaram B". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 09 Dec. 2024. Web. 21 Dec. 2024. < https://repository.mouau.edu.ng/work/view/the-evaluation-of-hypoglycemic-and-hypolipidemic-potentials-of-sweet-potato-on-a-wistar-albino-rat-okoroafor-chizaram-b-7-2 >.
BLESSING, CHIZARAM. "The Evaluation Of Hypoglycemic And Hypolipidemic Potentials Of Sweet Potato On A Wistar Albino Rat:- Okoroafor Chizaram B" Repository.mouau.edu.ng (2024). Accessed 21 Dec. 2024. https://repository.mouau.edu.ng/work/view/the-evaluation-of-hypoglycemic-and-hypolipidemic-potentials-of-sweet-potato-on-a-wistar-albino-rat-okoroafor-chizaram-b-7-2