The Effect of Methanol Seed Extract of Water Melon on Serum Electrolyte Balance in Dihydrotestosterol-Estradiol Velerate Induced Benign Prostatic Hyperplasia in male Wister Rat:- Ukpabi samuel. O

UKPABI SAMUEL ONYEKACHI | 89 pages (16242 words) | Projects

ABSTRACT

The acute, toxicity, phytochemical and effect methanol extract of Citrullus lanatus on PSA level and serum electrolyte were investigated using standard methods. The result of the phytochemical analysis of Citrullus lanatus showed high levels of flavonoid, saponin and reducing sugar. The LD50 was gotten at 500mg/kgbwt. The relative heart, kidney, lungs weight showed no p>0.05 significant difference. There was significant p<0.05 in relative prostate weight of disease control group when compared with other treated group when compared with other treated group while the relative testes significantly (p<0.05) decreased in disease control when compared with the normal and other treatment groups. The result of PSA level showed significant (p<0.05) increase in disease control when compared with other treatment groups. The serum electrolyte result showed that the level of sodium increased (p<0.05) significantly in disease relative to the normal control and groups treated with crude extract of a Citrullus lanatus. There w'as no (p>0.05) significant difference in chloride concentration between the treatment groups. The result also showed significant (p<0.05) decrease in potassium in disease and disease control w'hen compared with group treated with 400mg/kg but the level of Bicarbonate also decreased (p<0.05) significantly in disease control when compared with 200mg/kgbwt. The result show that Citrullus lanatus contain phytochemical that have the ability to reduce PSA and prostate weight relief of symptom of BPH, Thus The pharmacological efficacy of the extracts is believed to be due to synergistic effect of several compounds such as Flavonoids, Saponin, Oxalate

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APA

UKPABI, O (2024). The Effect of Methanol Seed Extract of Water Melon on Serum Electrolyte Balance in Dihydrotestosterol-Estradiol Velerate Induced Benign Prostatic Hyperplasia in male Wister Rat:- Ukpabi samuel. O. Repository.mouau.edu.ng: Retrieved Jun 18, 2024, from https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-seed-extract-of-water-melon-on-serum-electrolyte-balance-in-dihydrotestosterol-estradiol-velerate-induced-benign-prostatic-hyperplasia-in-male-wister-rat-ukpabi-samuel-o-7-2

MLA 8th

ONYEKACHI, UKPABI. "The Effect of Methanol Seed Extract of Water Melon on Serum Electrolyte Balance in Dihydrotestosterol-Estradiol Velerate Induced Benign Prostatic Hyperplasia in male Wister Rat:- Ukpabi samuel. O" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 17 May. 2024, https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-seed-extract-of-water-melon-on-serum-electrolyte-balance-in-dihydrotestosterol-estradiol-velerate-induced-benign-prostatic-hyperplasia-in-male-wister-rat-ukpabi-samuel-o-7-2. Accessed 18 Jun. 2024.

MLA7

ONYEKACHI, UKPABI. "The Effect of Methanol Seed Extract of Water Melon on Serum Electrolyte Balance in Dihydrotestosterol-Estradiol Velerate Induced Benign Prostatic Hyperplasia in male Wister Rat:- Ukpabi samuel. O". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 17 May. 2024. Web. 18 Jun. 2024. < https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-seed-extract-of-water-melon-on-serum-electrolyte-balance-in-dihydrotestosterol-estradiol-velerate-induced-benign-prostatic-hyperplasia-in-male-wister-rat-ukpabi-samuel-o-7-2 >.

Chicago

ONYEKACHI, UKPABI. "The Effect of Methanol Seed Extract of Water Melon on Serum Electrolyte Balance in Dihydrotestosterol-Estradiol Velerate Induced Benign Prostatic Hyperplasia in male Wister Rat:- Ukpabi samuel. O" Repository.mouau.edu.ng (2024). Accessed 18 Jun. 2024. https://repository.mouau.edu.ng/work/view/the-effect-of-methanol-seed-extract-of-water-melon-on-serum-electrolyte-balance-in-dihydrotestosterol-estradiol-velerate-induced-benign-prostatic-hyperplasia-in-male-wister-rat-ukpabi-samuel-o-7-2

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