ABSTRACT
In the present scenario of
environment consciousness, the new quality requirements not only emphasize on
the intrinsic functionality and long service life of the product but also
production process that is environment friendly. Copper nanoparticles (CuNPs)
were synthesized using a combination of aqueous extract of Xauclea latifolia
and 0.15g of copper sulphate (CuSOj) solution to obtain concentrations of 1
OOOmg-lOOOOmg. Characterization of the particles was done b\ I'V-Vis
spectroscopy. Fourier transform infrared (FT1R), Scanning Electron Microscopy
(SEM) and the X-ray Diffraction(XRD) average crystallite size was found to be
79nm. In this stud}, aqueous extract of leaves of Nauclea latifolia were
investigated for antibacterial activity using the standard agar well diffusion
technique against four clinical isolates (Staphylococcus epidermis, Proteus
mirabilis, Salmonella typhi and Streptococcos pneumonia.}. The Minimum
Inhibitory Concentration (MIC) was achieved by microbroth dilution and was also
determined by plate assay of chlorophenicle. Characterization by UVvisible
spectrometry revealed peak absorbance of 287 nm, while FT1R showed the presence
of fi\e functional groups which shows different stretches of bonds shown at
different peaks; the absorption band at 3276.3cm'1 indicates the presence of
O-H of an alcohol. The absorption band at 2918.5 and 2851.4 cm'1 show's the
presence of C-H of akyl groups. The peaks at 1722.0cm'1 shows the presence of
C=O of aldehydes. The band at 1602.8 cm'1 indicates the presence of C=C of
alkene. The band at 1021.8 cm'1 indicates the presence of C-0 of alcohols.The
data from this study indicate the potential of copper nanoparticle of Nanclea
latifolia as a suitable alternative antibacterial agent for incorporation into
orthodox medicine in health care delivery in Nigeria.
JOHN, U (2023). Secondary Metabolites from the Leaves Extract of Nauclea latifolia as a Reducing and Stabilizing Agent in the Synthesis of Copper Nanoparticles:- John Victoria U.. Repository.mouau.edu.ng: Retrieved Nov 23, 2024, from https://repository.mouau.edu.ng/work/view/secondary-metabolites-from-the-leaves-extract-of-nauclea-latifolia-as-a-reducing-and-stabilizing-agent-in-the-synthesis-of-copper-nanoparticles-john-victoria-u-7-2
UZOCHI, JOHN. "Secondary Metabolites from the Leaves Extract of Nauclea latifolia as a Reducing and Stabilizing Agent in the Synthesis of Copper Nanoparticles:- John Victoria U." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 11 Dec. 2023, https://repository.mouau.edu.ng/work/view/secondary-metabolites-from-the-leaves-extract-of-nauclea-latifolia-as-a-reducing-and-stabilizing-agent-in-the-synthesis-of-copper-nanoparticles-john-victoria-u-7-2. Accessed 23 Nov. 2024.
UZOCHI, JOHN. "Secondary Metabolites from the Leaves Extract of Nauclea latifolia as a Reducing and Stabilizing Agent in the Synthesis of Copper Nanoparticles:- John Victoria U.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 11 Dec. 2023. Web. 23 Nov. 2024. < https://repository.mouau.edu.ng/work/view/secondary-metabolites-from-the-leaves-extract-of-nauclea-latifolia-as-a-reducing-and-stabilizing-agent-in-the-synthesis-of-copper-nanoparticles-john-victoria-u-7-2 >.
UZOCHI, JOHN. "Secondary Metabolites from the Leaves Extract of Nauclea latifolia as a Reducing and Stabilizing Agent in the Synthesis of Copper Nanoparticles:- John Victoria U." Repository.mouau.edu.ng (2023). Accessed 23 Nov. 2024. https://repository.mouau.edu.ng/work/view/secondary-metabolites-from-the-leaves-extract-of-nauclea-latifolia-as-a-reducing-and-stabilizing-agent-in-the-synthesis-of-copper-nanoparticles-john-victoria-u-7-2