ABSTRACT
The
study investigated phytochemical and membrane stabilizing activity Anonma
muricata leaf. The phytochemical analysis was carried out using standard drug.
The membrane stabilizing activity was studied using rat’s erythrocytes against
a standard drug. The phytochemical analysis revealed the presence of high
levels flavonoids, saponins, reducing sugar, phenols, tannins and oxalates, but
trace amount ofterpenes, alkaloids, phytate and steroid. The methanol extract
ofthe leaves of Annona muricata showed that it can stabilize rat erythrocyte
membrane against hypotonic induced lyses. It showed a percentage membrane
stabilizing effect which ranged between 33.62+0.68 to 81.53±0.84 the result
showed a dose dependent effect. The presence of alkaloid, saponins, tannins,
flavonoid could be responsible for the membrane stabilizing properties
justifying the ethnomedical applications of Annona muricata leaf. Thus, further
advance research is necessary to isolate and characterize the chemical
compounds responsible for the therapeutic activities ofthe plant.
AKO, A (2024). “Phytochemicals and Membrane Stabilizing Effect of Methanol Extracts of Anonnamuricata Leaves:- Ako, Linda U. Repository.mouau.edu.ng: Retrieved Nov 05, 2024, from https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonnamuricata-leaves-ako-linda-u-7-2
AKO, AKO. "“Phytochemicals and Membrane Stabilizing Effect of Methanol Extracts of Anonnamuricata Leaves:- Ako, Linda U" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 17 May. 2024, https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonnamuricata-leaves-ako-linda-u-7-2. Accessed 05 Nov. 2024.
AKO, AKO. "“Phytochemicals and Membrane Stabilizing Effect of Methanol Extracts of Anonnamuricata Leaves:- Ako, Linda U". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 17 May. 2024. Web. 05 Nov. 2024. < https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonnamuricata-leaves-ako-linda-u-7-2 >.
AKO, AKO. "“Phytochemicals and Membrane Stabilizing Effect of Methanol Extracts of Anonnamuricata Leaves:- Ako, Linda U" Repository.mouau.edu.ng (2024). Accessed 05 Nov. 2024. https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonnamuricata-leaves-ako-linda-u-7-2