ABSTRACT
The study
investigated phytochemical and membrane stabilizing activity Anonma minicata
leaf. The phytochemical analysis was carried out using standard drug. The
membrane stabilizing activity was studied using rat’s erythrocytes against a
standard drug. The phytochemical analysis revealed the presence of high levels
flavonoids, saponins, reducing sugar, phenols, tannins and oxalates, but trace
amount ofterpenes, alkaloids, phytate and steroid. The methanol extract ofthe
leaves ofAnnona muricata showed that it can stabilize rat erythrocyte membrane
against hypotonic induced lyses. It showed a percentage membrane stabilizing effect
which ranged between 33.62±0.68 to 81.53±0.84 the result showed a dose
dependent effect. The presence of alkaloid, saponins, tannins, flavonoid could
be responsible for the membrane stabilizing properties justifying the
ethnomedical applications ofAnnona nniricata leaf. Thus, further advance
research is necessary to isolate and characterize the chemical compounds
responsible for the therapeutic activities ofthe plant.
AKO, A (2024). Phytochemicals And Membrane Stabilizing Effect Of Methanol Extracts Of Anonna Nturicata Leaves On Red Blood Cell Membrane Of Wister Rats:- Ako, Linda U. Repository.mouau.edu.ng: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonna-nturicata-leaves-on-red-blood-cell-membrane-of-wister-rats-ako-linda-u-7-2
AKO, AKO. "Phytochemicals And Membrane Stabilizing Effect Of Methanol Extracts Of Anonna Nturicata Leaves On Red Blood Cell Membrane Of Wister Rats:- Ako, Linda U" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 29 Feb. 2024, https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonna-nturicata-leaves-on-red-blood-cell-membrane-of-wister-rats-ako-linda-u-7-2. Accessed 24 Nov. 2024.
AKO, AKO. "Phytochemicals And Membrane Stabilizing Effect Of Methanol Extracts Of Anonna Nturicata Leaves On Red Blood Cell Membrane Of Wister Rats:- Ako, Linda U". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 29 Feb. 2024. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonna-nturicata-leaves-on-red-blood-cell-membrane-of-wister-rats-ako-linda-u-7-2 >.
AKO, AKO. "Phytochemicals And Membrane Stabilizing Effect Of Methanol Extracts Of Anonna Nturicata Leaves On Red Blood Cell Membrane Of Wister Rats:- Ako, Linda U" Repository.mouau.edu.ng (2024). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/phytochemicals-and-membrane-stabilizing-effect-of-methanol-extracts-of-anonna-nturicata-leaves-on-red-blood-cell-membrane-of-wister-rats-ako-linda-u-7-2