ABSTRACT

Bombax buonoponenzes (P.Beauv) is a medicinal plant used in treating migraine headache and it is used also to increase lactation in nursing mothers as well as other uses. The present study was aimed at investigating the nephroprotective activity of methanol leave extract of Bombax buonopozens in wistar albino rats. The Biochemical parameters evaluated includes urea and creatinine. From the result, it was revealed that prolong use of methanol extract of Bombax buonopozense leaves extract causes significant decreases (p<0.05) in creatinine and urea level suggested Bombax buonoponenzes plays a vital role in detoxification and nephro-protection

TABLE OF CONTENTS

TITLE PAGE i

CERTIFICATION ii

DEDICATION iii

ACKNOWLEDGEMENT iv

TABLE OF CONTENTS v

LIST OF TABLES vi

LIST OF FIGURES vii

ABSTRACT viii

CHAPTER ONE

1.0 Introduction 1

1.1   Aim of the Study 4

1.2   Objective of the Study 4

1.3   Justification of the Study 4

1.4   Scope of the Study 5

CHAPTER TWO

2.1 Literature Review 6

2.2       Origin 10

2.3 Botanical Description Of Bombax Buonoponenzes (P.Beauv)             10

2.4    Uses 10

CHAPTER THREE

Materials And Method

3.1      Plant Sample                                    13

3.2     Preparation Of The Extract 13

3.3     Experimental Animals 14

3.4     Experimental Design 14

3.5     Biochemical Estimation 15

CHAPTER FOUR

4.0       Result 16

4.1      Nephroprotective Effect of Methanol Leaf extract o Bombax buonopoenses

           (P-Beauv) on Serum Creatinine level of Paracetamol induced Wister Rats                22

CHAPTER FIVE

Conclusion And Recommendation

5.3     Recommendation 18

References

Appendix