“Evaluation of Antioxidant and Antimicrobial activities of ethanolic root extract ofAmaranthus spinosus (Linn) on selected clinical isolate:- Chidi, Goodluck
ABSTRACT
Medicinal plants have been found to play a
significant role in the treatment of human ailments due to the resistance
nature of synthetic drugs aside been very expensive. One of the leading
medicinal plant found to have therapeutic power is Amaranthus spinosus Linn.
This present study is aimed at investigating the antioxidant and antimicrobial
activities of ethanolic root extract of Amaranthus spinosus Linn. The
antioxidant activity of root extract of Amaranthus spinosus was accessed by in-
vitro experimental parameters such as DPPH (2,2-Diphenly -1- picrylhydrazyl)
free radical scavenging activity and Nitric oxide radical assay and Anti-lipid
peroxidation. In this study, DPPH was found to be concentration-dependent. The
result showed that Amaranthus spinosus ethanolic root extract have showed
potent in vitro antioxidant activity that may be attributed to the phenolic
compounds present. The ethanolic root extract of Amaranthus spinosus was
evaluated for antimicrobial activity against 6 bacteria’s such as (Proteus
mirabillis, Streptococcus pneumoniae, Proteus aureginosa, Lactococcus bacillus,
Klebsiella pnueumoniae, and Staphylococcus aureus') the in -vitro antimicrobial
activity was performed by Agar Disc Diffusion method with Potato Dextrose Agar
(PDA). The extract of lOOOmg showed the highest inhibitory zone
(33.00mm±1.00mm) on Staphylococcus aureus, while the extract of 62.5mg showed
the least inhibitory zone (1.66mm±5.77mm) on Proteus mirabillis. All the
organisms were susceptible to the plant extracts used for the antimicrobial
test. This study strongly recommends the use of Amaranthus spinosus ethanolic
root extracts as an Antimicrobial agent and can be used to cure many ailments
caused by these microorganisms.
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CHIDI, C (2023). “Evaluation of Antioxidant and Antimicrobial activities of ethanolic root extract ofAmaranthus spinosus (Linn) on selected clinical isolate:- Chidi, Goodluck. Repository.mouau.edu.ng: Retrieved Nov 23, 2024, from https://repository.mouau.edu.ng/work/view/evaluation-of-antioxidant-and-antimicrobial-activities-of-ethanolic-root-extract-ofamaranthus-spinosus-linn-on-selected-clinical-isolate-chidi-goodluck-7-2
CHIDI, CHIDI. "“Evaluation of Antioxidant and Antimicrobial activities of ethanolic root extract ofAmaranthus spinosus (Linn) on selected clinical isolate:- Chidi, Goodluck" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 31 Oct. 2023, https://repository.mouau.edu.ng/work/view/evaluation-of-antioxidant-and-antimicrobial-activities-of-ethanolic-root-extract-ofamaranthus-spinosus-linn-on-selected-clinical-isolate-chidi-goodluck-7-2. Accessed 23 Nov. 2024.
CHIDI, CHIDI. "“Evaluation of Antioxidant and Antimicrobial activities of ethanolic root extract ofAmaranthus spinosus (Linn) on selected clinical isolate:- Chidi, Goodluck". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 31 Oct. 2023. Web. 23 Nov. 2024. < https://repository.mouau.edu.ng/work/view/evaluation-of-antioxidant-and-antimicrobial-activities-of-ethanolic-root-extract-ofamaranthus-spinosus-linn-on-selected-clinical-isolate-chidi-goodluck-7-2 >.
CHIDI, CHIDI. "“Evaluation of Antioxidant and Antimicrobial activities of ethanolic root extract ofAmaranthus spinosus (Linn) on selected clinical isolate:- Chidi, Goodluck" Repository.mouau.edu.ng (2023). Accessed 23 Nov. 2024. https://repository.mouau.edu.ng/work/view/evaluation-of-antioxidant-and-antimicrobial-activities-of-ethanolic-root-extract-ofamaranthus-spinosus-linn-on-selected-clinical-isolate-chidi-goodluck-7-2