"Effects of the Ethanol Extract of the Leaves of A. muricata on Red Blood Cell (RBC) Count of Aspirin-ulcerated Rats:- Nwoche Victor U.
ABSTRACT
Natural products especially those derived from
plants have been used to help mankind sustain health since the dawn of medicine.
Over the past century, the phytochemicals in plants have been a pivotal
pipeline for pharmaceutical discoveries. The objectives of this work were to
examine the phytochemical constituents, acute toxicity and lethality and effect
of the ethanol extract of the leaves of A. muricata on the red blood cell (RBC)
count of aspirin-ulcerated rats. The qualitative phytochemical analyses
revealed the presence of alkaloids, flavonoids, tannins, saponins,
carbohydrates, glycosides, proteins, steroids, tcrpenoids and fats and oil.
Resins, reducing sugars and acidic compounds were not detected in the extract.
The extract was found to be safe even at a dose as high as 5000 mg/kg body
weight (b.w). The extract at the tested doses (100,200 and 400 mg/kg b. w)
significantly (p < 0.05) and dose-dependently increased the RBC count of the
rats in the test groups compared to the value obtained for the rats in the
ulcer-untreated group. These implies that the leaves of A. muricata may serve
as origin of anti-ulcer drug(s) in future .
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NWOCHE, U (2024). "Effects of the Ethanol Extract of the Leaves of A. muricata on Red Blood Cell (RBC) Count of Aspirin-ulcerated Rats:- Nwoche Victor U.. Repository.mouau.edu.ng: Retrieved Nov 21, 2024, from https://repository.mouau.edu.ng/work/view/effects-of-the-ethanol-extract-of-the-leaves-of-a-muricata-on-red-blood-cell-rbc-count-of-aspirin-ulcerated-rats-nwoche-victor-u-7-2
UZOMA, NWOCHE. ""Effects of the Ethanol Extract of the Leaves of A. muricata on Red Blood Cell (RBC) Count of Aspirin-ulcerated Rats:- Nwoche Victor U." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 25 Mar. 2024, https://repository.mouau.edu.ng/work/view/effects-of-the-ethanol-extract-of-the-leaves-of-a-muricata-on-red-blood-cell-rbc-count-of-aspirin-ulcerated-rats-nwoche-victor-u-7-2. Accessed 21 Nov. 2024.
UZOMA, NWOCHE. ""Effects of the Ethanol Extract of the Leaves of A. muricata on Red Blood Cell (RBC) Count of Aspirin-ulcerated Rats:- Nwoche Victor U.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 25 Mar. 2024. Web. 21 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effects-of-the-ethanol-extract-of-the-leaves-of-a-muricata-on-red-blood-cell-rbc-count-of-aspirin-ulcerated-rats-nwoche-victor-u-7-2 >.
UZOMA, NWOCHE. ""Effects of the Ethanol Extract of the Leaves of A. muricata on Red Blood Cell (RBC) Count of Aspirin-ulcerated Rats:- Nwoche Victor U." Repository.mouau.edu.ng (2024). Accessed 21 Nov. 2024. https://repository.mouau.edu.ng/work/view/effects-of-the-ethanol-extract-of-the-leaves-of-a-muricata-on-red-blood-cell-rbc-count-of-aspirin-ulcerated-rats-nwoche-victor-u-7-2