Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacinulcerated Rats:- Nkwocha, Doreen Ebere
ABSTRACT
Plants have been the basis for
trado-medical treatments through much of human history and such traditional
medicine is still widely in use today such as the leaves of M. paradisiaca. The
objectives of this work were to examine the phytochemical constituents, acute
toxicity and lethality and effect of the methanol extract of the leaves of M.
paradisiaca on red blood cell count of indomethacin-ulccrated rats. The
preliminary phytochemical screening revealed that the plant leaves contained
alkaloids, flavonoids, tannins, saponins, carbohydrates, reducing sugars,
proteins, steroids, terpenoids and fats and oil but resins, glycosides and
acidic compounds were not detected. The extract was found to be safe at a dose
as high as 5000 mg/kg body weight (b.w). The extract at the tested doses (100,
200 and 400 mg/kgb.w) significantly (p < 0.05) and dose-dependently
increased the red blood cell count ofthe rats in the test groups when compared
to the value obtained for the rats in the ulcer-untreated group. The effect
ofthe 400 mg/kg b.w of the extract was similar to that ofthe standard
anti-ulcer drug, famotidine at the dose of 50 mg/kg b.w. The results indicate
that the methanol extract ofthe leaves of M. paradisiaca contains some
pharmacological active principles which may raise the red blood cell count in ulcerated
rats.
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NKWOCHA, E (2023). Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacinulcerated Rats:- Nkwocha, Doreen Ebere. Repository.mouau.edu.ng: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacinulcerated-rats-nkwocha-doreen-ebere-7-2
EBERE, NKWOCHA. "Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacinulcerated Rats:- Nkwocha, Doreen Ebere" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 18 Oct. 2023, https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacinulcerated-rats-nkwocha-doreen-ebere-7-2. Accessed 24 Nov. 2024.
EBERE, NKWOCHA. "Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacinulcerated Rats:- Nkwocha, Doreen Ebere". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 18 Oct. 2023. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacinulcerated-rats-nkwocha-doreen-ebere-7-2 >.
EBERE, NKWOCHA. "Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacinulcerated Rats:- Nkwocha, Doreen Ebere" Repository.mouau.edu.ng (2023). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacinulcerated-rats-nkwocha-doreen-ebere-7-2