Effect Of The Ethanol Extract Of The Leaves Of Annona Muriccitci On The Lipid Peroxidation Of Aspirin-Ulcerated Rats:- Agu, Favour .A.
ABSTRACT
Many plains and plant-derived
products have been screened for their medicinal purposes with some having
anti-inflammatory and anti-ulcer effects among others. I he aim oi this work
was to determine the effect ofthe ethanol extract of the leaves ol A. muricata
on malondialdehyde (MDA) concentration of aspirinulcerated rats. 1 he
preliminary phytochemical screening revealed that the extract contained
alkaloids, flavonoids, tannins, saponins, carbohydrates, glycosides, proteins,
steroids, terpenoids and fats and oil but reducing sugars, acidic compounds and
resins were not delected in the extract. The extract al the graded doses [100,
200 and 400 mg/kg body weight (b.w)J caused significant (p < 0.05) and
dose-dependent decreases in the MDA concentrations of the rats in the test
group when compared to the value obtained for the rats in the control group.
The effect of the 400 mg/kg b.w of the extract was similar to that of the
standard anti-ulcer drug, ranitidine at the dose of 150 mg/kg b.w. The results
indicate that the ethanol extract of the leaves of A. mwicata contains some
pharmacologically active principles which justify the use of leaves of the
plant in traditional medicine for the treatment ol gastric ulcer.
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MICHAEL, U (2023). Effect Of The Ethanol Extract Of The Leaves Of Annona Muriccitci On The Lipid Peroxidation Of Aspirin-Ulcerated Rats:- Agu, Favour .A.. Repository.mouau.edu.ng: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-the-ethanol-extract-of-the-leaves-of-annona-muriccitci-on-the-lipid-peroxidation-of-aspirin-ulcerated-rats-agu-favour-a-7-2
UNIVERSITY, MICHAEL. "Effect Of The Ethanol Extract Of The Leaves Of Annona Muriccitci On The Lipid Peroxidation Of Aspirin-Ulcerated Rats:- Agu, Favour .A." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 18 Oct. 2023, https://repository.mouau.edu.ng/work/view/effect-of-the-ethanol-extract-of-the-leaves-of-annona-muriccitci-on-the-lipid-peroxidation-of-aspirin-ulcerated-rats-agu-favour-a-7-2. Accessed 24 Nov. 2024.
UNIVERSITY, MICHAEL. "Effect Of The Ethanol Extract Of The Leaves Of Annona Muriccitci On The Lipid Peroxidation Of Aspirin-Ulcerated Rats:- Agu, Favour .A.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 18 Oct. 2023. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-the-ethanol-extract-of-the-leaves-of-annona-muriccitci-on-the-lipid-peroxidation-of-aspirin-ulcerated-rats-agu-favour-a-7-2 >.
UNIVERSITY, MICHAEL. "Effect Of The Ethanol Extract Of The Leaves Of Annona Muriccitci On The Lipid Peroxidation Of Aspirin-Ulcerated Rats:- Agu, Favour .A." Repository.mouau.edu.ng (2023). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/effect-of-the-ethanol-extract-of-the-leaves-of-annona-muriccitci-on-the-lipid-peroxidation-of-aspirin-ulcerated-rats-agu-favour-a-7-2