Effect Of Oral Administration Of Methanolic Leaf Extract Of Tectona Grandis Level Of Iron, Calcium And Zinc In Normal And Immune Compromise Rat.
ABSTRACT
The effect of oral administration of methanolic extract of Tectona grandis level on iron, calcium and Zinc of normal and immune compromised rats were studied, they were 4 groups of test samples and a normal control group. the 4 test were fed as follows Group 1 suppressed + methanolic tectona, Group 2 suppressed + standard drug, Group 3 Normal rat + methanolic tectona , Group 4 suppressed not treated administrated and control group had normal rat chow . From the analysis of the result, effects of methanolic extract of Tectona grandis on serum calcium level was seen higher in Group 1 (10.37+ 0.38) , Group 3 10.20 + 0.18) and Group 4 (10.30+0.56) but dropped in Group 2 (9.82+0.33) while control group remain this suggest that methanolic extract of Tectona Grandis increased the serum calcium level in suppressed rats, while standard drug reduced serum calcium level. Effects of methanolic extract of Tectona Grandis serum iron level showed Group 3 (181.25 +37.15) Group 2 (754.25 +178.86) and Group 1(715.50 +163.19) had increased serum iron level while group 4(229.25+22.11) had reduced iron levels compared to the control group which also reduced. This suggested methanolic extract of Tectona grandis drastically increased iron for erythropoetic ability (Red blood cell formation). Effects of methanolic extract of Tectona grandis on serum zinc showed Group 2(230+16.51), Group 4 (202.50+40.51) and Group 3 (174.50+7.14) had higher zinc load, but Group 1 (166.00+10.92) had lower zinc load compared to the control group which also have lower zinc load, this suggestive that tectona grandis reduced serum zinc level in rats.
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ALAUKWU, M (2021). Effect Of Oral Administration Of Methanolic Leaf Extract Of Tectona Grandis Level Of Iron, Calcium And Zinc In Normal And Immune Compromise Rat.. Repository.mouau.edu.ng: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-oral-administration-of-methanolic-leaf-extract-of-tectona-grandis-level-of-iron-calcium-and-zinc-in-normal-and-immune-compromise-rat-7-2
M., ALAUKWU. "Effect Of Oral Administration Of Methanolic Leaf Extract Of Tectona Grandis Level Of Iron, Calcium And Zinc In Normal And Immune Compromise Rat." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 23 Jun. 2021, https://repository.mouau.edu.ng/work/view/effect-of-oral-administration-of-methanolic-leaf-extract-of-tectona-grandis-level-of-iron-calcium-and-zinc-in-normal-and-immune-compromise-rat-7-2. Accessed 24 Nov. 2024.
M., ALAUKWU. "Effect Of Oral Administration Of Methanolic Leaf Extract Of Tectona Grandis Level Of Iron, Calcium And Zinc In Normal And Immune Compromise Rat.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 23 Jun. 2021. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-oral-administration-of-methanolic-leaf-extract-of-tectona-grandis-level-of-iron-calcium-and-zinc-in-normal-and-immune-compromise-rat-7-2 >.
M., ALAUKWU. "Effect Of Oral Administration Of Methanolic Leaf Extract Of Tectona Grandis Level Of Iron, Calcium And Zinc In Normal And Immune Compromise Rat." Repository.mouau.edu.ng (2021). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/effect-of-oral-administration-of-methanolic-leaf-extract-of-tectona-grandis-level-of-iron-calcium-and-zinc-in-normal-and-immune-compromise-rat-7-2