Effect of Hydro Ethanolic Extract of Amaranthus hybridus on Nitric Oxide and Malondialdehyde levels in Thioacetamide Intoxicated Wistar Rat:- Onyenkwere Queen
ABSTRACT
The study was designed to determine the effect
of hydro alcoholic extract of Amaranthus hybridus on nitric oxide and
malondialdehyde level of thioacetamide intoxicated wistar rat. For this
purpose, 36 male wistar rats were divided into 6 groups (n=6). Group (1)
intoxicated with thioacetamide and treated with silymarin; Group (2) healthy
control with no intoxication and treatment; Group (3) intoxicated with
thioacetamide and treated with hydro alcoholic extract of Amaranthus hybridus
at dose of (lOOmg/kg); Group (4) intoxicated with thioacetamide and treated
with hydro alcoholic extract ofAmaranthus hybridus at dose of (200mg/kg); Group
(5) intoxicated with thioacetamide and treated with hydro alcoholic extract of
Amaranthus hybridus at dose of (400mg/kg); Group (6) intoxicated with
thioacetamide with no treatment. The liver MDA content of rat in Group (6)
which is the negative control was significantly (p<0.05) higher than other
group, and the liver NO content was significantly (p<0.05) lower than other
groups. This study indicates the valuable effect of Amaranthus hybridus
antioxidant agents against oxidative stress induced by TAA.
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MICHAEL, U (2024). Effect of Hydro Ethanolic Extract of Amaranthus hybridus on Nitric Oxide and Malondialdehyde levels in Thioacetamide Intoxicated Wistar Rat:- Onyenkwere Queen. Repository.mouau.edu.ng: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-hydro-ethanolic-extract-of-amaranthus-hybridus-on-nitric-oxide-and-malondialdehyde-levels-in-thioacetamide-intoxicated-wistar-rat-onyenkwere-queen-7-2
UNIVERSITY, MICHAEL. "Effect of Hydro Ethanolic Extract of Amaranthus hybridus on Nitric Oxide and Malondialdehyde levels in Thioacetamide Intoxicated Wistar Rat:- Onyenkwere Queen" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 26 Feb. 2024, https://repository.mouau.edu.ng/work/view/effect-of-hydro-ethanolic-extract-of-amaranthus-hybridus-on-nitric-oxide-and-malondialdehyde-levels-in-thioacetamide-intoxicated-wistar-rat-onyenkwere-queen-7-2. Accessed 24 Nov. 2024.
UNIVERSITY, MICHAEL. "Effect of Hydro Ethanolic Extract of Amaranthus hybridus on Nitric Oxide and Malondialdehyde levels in Thioacetamide Intoxicated Wistar Rat:- Onyenkwere Queen". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 26 Feb. 2024. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-hydro-ethanolic-extract-of-amaranthus-hybridus-on-nitric-oxide-and-malondialdehyde-levels-in-thioacetamide-intoxicated-wistar-rat-onyenkwere-queen-7-2 >.
UNIVERSITY, MICHAEL. "Effect of Hydro Ethanolic Extract of Amaranthus hybridus on Nitric Oxide and Malondialdehyde levels in Thioacetamide Intoxicated Wistar Rat:- Onyenkwere Queen" Repository.mouau.edu.ng (2024). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/effect-of-hydro-ethanolic-extract-of-amaranthus-hybridus-on-nitric-oxide-and-malondialdehyde-levels-in-thioacetamide-intoxicated-wistar-rat-onyenkwere-queen-7-2