Effect Of Hibiscus Sabdariffa On Thioacetamide Lnduced Hepatocaricinoma On The Antioxidant And Hematololgical Parameters Of Wister Rats
ABSTRACT
The work is aimed at
investigating the effect of methanol extract of Hibiscus sabdariffa on
thiacetamide induced hepatocarcinoma on the antioxidant and hematological
parameters of wister rats over a 21 days period. The rats were divided into
three groups with four in each group. The first group which is the control
received feed and water throughout the period of the study, the second group
which is positive control received O.54m1 of thioacetamide alongside feed and
water and the third group which is the test group for the extract received
O.38m1 of leaf extract. The animal was observed for the period of the study
blood from the animal was collected for analysis such as RBC, TWBC, PVC, HB ,
were carried out and result obtained showed that there was significant decrease
or increase(P< 0.05) when the test group is compared with the positive
control group for the results obtained for RBC ,TWBC, PVC, HB, there was no
significant decrease or increase (P< 0.05).The result obtained are an
indication that the administration of plant extract to thioacetamide rats could
raise liver damage as stated in previous studies.it equally increases the rate
of lipid peroxidation.
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NWABUEZE, C (2021). Effect Of Hibiscus Sabdariffa On Thioacetamide Lnduced Hepatocaricinoma On The Antioxidant And Hematololgical Parameters Of Wister Rats. Repository.mouau.edu.ng: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-hibiscus-sabdariffa-on-thioacetamide-lnduced-hepatocaricinoma-on-the-antioxidant-and-hematololgical-parameters-of-wister-rats-7-2
CYNTHIA, NWABUEZE. "Effect Of Hibiscus Sabdariffa On Thioacetamide Lnduced Hepatocaricinoma On The Antioxidant And Hematololgical Parameters Of Wister Rats" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 30 Jun. 2021, https://repository.mouau.edu.ng/work/view/effect-of-hibiscus-sabdariffa-on-thioacetamide-lnduced-hepatocaricinoma-on-the-antioxidant-and-hematololgical-parameters-of-wister-rats-7-2. Accessed 24 Nov. 2024.
CYNTHIA, NWABUEZE. "Effect Of Hibiscus Sabdariffa On Thioacetamide Lnduced Hepatocaricinoma On The Antioxidant And Hematololgical Parameters Of Wister Rats". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 30 Jun. 2021. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-hibiscus-sabdariffa-on-thioacetamide-lnduced-hepatocaricinoma-on-the-antioxidant-and-hematololgical-parameters-of-wister-rats-7-2 >.
CYNTHIA, NWABUEZE. "Effect Of Hibiscus Sabdariffa On Thioacetamide Lnduced Hepatocaricinoma On The Antioxidant And Hematololgical Parameters Of Wister Rats" Repository.mouau.edu.ng (2021). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/effect-of-hibiscus-sabdariffa-on-thioacetamide-lnduced-hepatocaricinoma-on-the-antioxidant-and-hematololgical-parameters-of-wister-rats-7-2