Effect Of Aqueous Leaves Extract Of Loranthus Micranthus Linn On Oral Chronic Administration Of Artemether-Lumefantrine (Coartem) On The Liver Of Male Wistar Rats.
ABSTRACT
This study was carried out to evaluate the effect of aqueous
leaves extract of Loranthus micranthus on oral chronic administration of
Coartem on the liver of male wistar rats. Acute toxicity study of the extract
was evaluated but no death was recorded even at 5000mg/kg. Sixteen (16) male
wistar rats were used and they were divided randomly into four groups. Group 1
served as the normal control, Group 2 received only aqueous leaves extract of
Loranthus micranthus (150mg/kg), Group 3 received coartem only (27mg/kg) and
Group 4 received coartem (27mg/kg) and the aqueous leaves extract of Loranthus
micranthu (150mg/kg). Duration of the study lasted for three weeks. Antioxidant
assays and level of lipid peroxidation were investigated. The result of the
study indicated a significant increase (p
0.0
MUONEKE, S (2021). Effect Of Aqueous Leaves Extract Of Loranthus Micranthus Linn On Oral Chronic Administration Of Artemether-Lumefantrine (Coartem) On The Liver Of Male Wistar Rats.. Repository.mouau.edu.ng: Retrieved Apr 27, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-aqueous-leaves-extract-of-loranthus-micranthus-linn-on-oral-chronic-administration-of-artemether-lumefantrine-coartem-on-the-liver-of-male-wistar-rats-7-2
SOMTOCHUKWU, MUONEKE. " Effect Of Aqueous Leaves Extract Of Loranthus Micranthus Linn On Oral Chronic Administration Of Artemether-Lumefantrine (Coartem) On The Liver Of Male Wistar Rats." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 19 Nov. 2021, https://repository.mouau.edu.ng/work/view/effect-of-aqueous-leaves-extract-of-loranthus-micranthus-linn-on-oral-chronic-administration-of-artemether-lumefantrine-coartem-on-the-liver-of-male-wistar-rats-7-2. Accessed 27 Apr. 2024.
SOMTOCHUKWU, MUONEKE. " Effect Of Aqueous Leaves Extract Of Loranthus Micranthus Linn On Oral Chronic Administration Of Artemether-Lumefantrine (Coartem) On The Liver Of Male Wistar Rats.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 19 Nov. 2021. Web. 27 Apr. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-aqueous-leaves-extract-of-loranthus-micranthus-linn-on-oral-chronic-administration-of-artemether-lumefantrine-coartem-on-the-liver-of-male-wistar-rats-7-2 >.
SOMTOCHUKWU, MUONEKE. " Effect Of Aqueous Leaves Extract Of Loranthus Micranthus Linn On Oral Chronic Administration Of Artemether-Lumefantrine (Coartem) On The Liver Of Male Wistar Rats." Repository.mouau.edu.ng (2021). Accessed 27 Apr. 2024. https://repository.mouau.edu.ng/work/view/effect-of-aqueous-leaves-extract-of-loranthus-micranthus-linn-on-oral-chronic-administration-of-artemether-lumefantrine-coartem-on-the-liver-of-male-wistar-rats-7-2