Diuretic and anti inflammatory effects of new boulidiia laevis (p. Beauv) tree of life leaf extracts on rat:- Ibe, Chinonso J
ABSTRACT
The present study investigates the
anti-inflammatory and diuretic ac-ivity of ethanoiic extracts of the leaf of
Newbouldia laevis. The ethanol leaf ex ract was administered intra-peritoneally
to the rats at doses of 18.25, 37.5, 75 150 and 300mg/kg body weight
respectively for the anti-inflammatory effect whe1 :! aspirin was used as a
positive control and normal saline for negative control. The average
inflammation decreased as time intervals increased. However, highest i hibition
was obtained with the extract of highest concentration (11.67± 1.53) for 300mg.
The diuretic effects was evaluated by measuring the urine volume. Th extract
produced a significant increase in urine volume at 30 and 150mgkg (6.62± 1.16
and 4.42±0.33) respectively with a significant difference (p<0.050.
furosenide was used as positive control and normal saline was used as negative
contrc!. These results show that ethanol leaf extract of Newbouldia leavis has
pote1 ·tial and significant anti-inflammatory and diuretic properties.
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CHINONSO, J (2024). Diuretic and anti inflammatory effects of new boulidiia laevis (p. Beauv) tree of life leaf extracts on rat:- Ibe, Chinonso J. Repository.mouau.edu.ng: Retrieved Apr 28, 2024, from https://repository.mouau.edu.ng/work/view/diuretic-and-anti-inflammatory-effects-of-new-boulidiia-laevis-p-beauv-tree-of-life-leaf-extracts-on-rat-ibe-chinonso-j-7-2
JECINTA, CHINONSO. "Diuretic and anti inflammatory effects of new boulidiia laevis (p. Beauv) tree of life leaf extracts on rat:- Ibe, Chinonso J" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 06 Mar. 2024, https://repository.mouau.edu.ng/work/view/diuretic-and-anti-inflammatory-effects-of-new-boulidiia-laevis-p-beauv-tree-of-life-leaf-extracts-on-rat-ibe-chinonso-j-7-2. Accessed 28 Apr. 2024.
JECINTA, CHINONSO. "Diuretic and anti inflammatory effects of new boulidiia laevis (p. Beauv) tree of life leaf extracts on rat:- Ibe, Chinonso J". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 06 Mar. 2024. Web. 28 Apr. 2024. < https://repository.mouau.edu.ng/work/view/diuretic-and-anti-inflammatory-effects-of-new-boulidiia-laevis-p-beauv-tree-of-life-leaf-extracts-on-rat-ibe-chinonso-j-7-2 >.
JECINTA, CHINONSO. "Diuretic and anti inflammatory effects of new boulidiia laevis (p. Beauv) tree of life leaf extracts on rat:- Ibe, Chinonso J" Repository.mouau.edu.ng (2024). Accessed 28 Apr. 2024. https://repository.mouau.edu.ng/work/view/diuretic-and-anti-inflammatory-effects-of-new-boulidiia-laevis-p-beauv-tree-of-life-leaf-extracts-on-rat-ibe-chinonso-j-7-2