ABSTRACT
This study
compare the performance of microscopy and rapid diagnostic tests (RDTs) in
diagnosing malaria. A total of 200 new intake students of Federal Government
College Ohafia, in Ohafia L.G.A. of Abia State referred to O’ event diagnostic
laboratory Umuahia who gave their consents were examined using microscopy and
RDTs. Thick and thin blood smears prepared on clean grease free slides from
venous blood aseptically collected from each student and stained with giemsa
stain were examined for the presence of malaria parasite. The serological
diagnosis was performed using CareStart'™ malaria HRP2 (P/) test kits and SD
Bioline malaria test kits following manufacturers instructions. Data were
analysed using Chi square. Prevalence rates recorded for malaria infection were
24%, 10.5% and 12.0% by microscopy, CareStart'™ malaria HRP2 (Pf) and SD
Bioline RDTs respectively. Chi-square test showed significant difference (P<0.03) between microscopy and RDTs. The male students were more infected (27.3%) than the female students (20.8%) with no significant difference (X?=0.83, P>0.05).
Prevalence in age group 9-11 years was observed to be highest with no
significant difference (X?=0.35, P>0.05) for both microscopy and RDTs.
CareStart'™ malaria HRP2 (2/) and SD Bioline malaria sensitivities were 90.5%
and 88.0% respectively and specificities were 97.1% and 97.6% respectively. The
need for the development of new, simple, quick, accurate, and cost-effective
diagnosis tests for determining the presence of malaria parasites can be
complemented by the use of RDTSs since the sensitivity and specificity results
of the two RDTs used in this study have shown their usefulness as a rapid and
simple tool for malaria diagnosis. Deployment of RDTs in school clinics by the
State Ministry of Health and other health related organizations especially
school clinics without access to microscopy is advised.
AUGUSTINE, A (2023). Comparison Of Microscopy And Rapid Diagnostic Tests In Screening The New Intake Students Of Federal Government College Ohafia, In Ohafia L. G. A Of Abia State, Nigeria. Repository.mouau.edu.ng: Retrieved Sep 08, 2024, from https://repository.mouau.edu.ng/work/view/comparison-of-microscopy-and-rapid-diagnostic-tests-in-screening-the-new-intake-students-of-federal-government-college-ohafia-in-ohafia-l-g-a-of-abia-state-nigeria-7-2
AUGUSTINE, AUGUSTINE. "Comparison Of Microscopy And Rapid Diagnostic Tests In Screening The New Intake Students Of Federal Government College Ohafia, In Ohafia L. G. A Of Abia State, Nigeria" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 14 Sep. 2023, https://repository.mouau.edu.ng/work/view/comparison-of-microscopy-and-rapid-diagnostic-tests-in-screening-the-new-intake-students-of-federal-government-college-ohafia-in-ohafia-l-g-a-of-abia-state-nigeria-7-2. Accessed 08 Sep. 2024.
AUGUSTINE, AUGUSTINE. "Comparison Of Microscopy And Rapid Diagnostic Tests In Screening The New Intake Students Of Federal Government College Ohafia, In Ohafia L. G. A Of Abia State, Nigeria". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 14 Sep. 2023. Web. 08 Sep. 2024. < https://repository.mouau.edu.ng/work/view/comparison-of-microscopy-and-rapid-diagnostic-tests-in-screening-the-new-intake-students-of-federal-government-college-ohafia-in-ohafia-l-g-a-of-abia-state-nigeria-7-2 >.
AUGUSTINE, AUGUSTINE. "Comparison Of Microscopy And Rapid Diagnostic Tests In Screening The New Intake Students Of Federal Government College Ohafia, In Ohafia L. G. A Of Abia State, Nigeria" Repository.mouau.edu.ng (2023). Accessed 08 Sep. 2024. https://repository.mouau.edu.ng/work/view/comparison-of-microscopy-and-rapid-diagnostic-tests-in-screening-the-new-intake-students-of-federal-government-college-ohafia-in-ohafia-l-g-a-of-abia-state-nigeria-7-2