ABSTRACT
Medicinal plants have shown to possess some
biological constituents that have significant effect in man. This study
undertook a comparative study on the antimicrobial activities of two herbal
mixtures (Goko and Clara bitter cleanser) and the crude extract of Tetrapleura
tetraptera (a traditional African food spice). Aqueous and ethanoic extracts of
Tetrapleura tetraptera were produced and use alongside the herbal mixtures for
antimicrobial activity against four bacterial pathogens (Staphylococcus aureus,
Escherichia coli, and Pseudomonas aeruginosa) and three fungal pathogens
(4spergillus, Penicillin and Candida albicans). Obtained resultsĀ· show higher
extract yield of 18.82% and 19.64% for Clara bitter cleanser and Goko cleanser
and 12.46% and 11.96% for the ethanol and water extracts of Tetrapleura
tetraptera respectively. Phytochemical screening results show high presence of
alkaloid and tlavonoids in the extracts and the mixtures showed moderate
presence of Saponin, Tanin, Steroids and glycosides. Antimicrobial activity of
the extract was in the range of 10.67mm to 13.67mmand13.33mm to 15.67mm against
the bacteria for aqueous and water extract respectively as against 12.67mm to
16.67mm (Clara cleanser) and 14.00mm to 16.33mm (Goko cleanser). Diameter of
inhibition of fungi was higher with ethanol extract of Tetrapleura tetraptera
(14.33mm to 16.33mm) as against13.00mm (Goko) and 12.67mm (Clara).
Comparatively, the ethanol extract of Tetrapleura tetraptera demonstrated
higher activity against all three testfungi (Aspergil/us, Penicillin and
Candida) than Goko and clara bitter cleanser while the herbal mixtures show
higher activity against Gram negative bacteria ( Escherichia coli, Salmonella,
Pseudomonas) both showed lower activity against the Gram positive
Staphylococcus aureus. There were variations in the antimicrobial activities of
the plant extracts and the herbal mixtures with relative potencies of 71.29% to
76.56% for the extract, 64.41 % to 73.47% for Clara bitter cleanser and 66.09%
to 72.31 % Goko cleanser. Our results reveal the importance of Tetrapleura
tetraptera for medicinal and food uses in local communities and its potential
for improving local livelihoods through its domestication.
CHINENYEKALU, C (2025). Comparative Study Of The Antimicrobial Activities Of Locally Sold Herbal Mixture And The Crude Extract Of Tetrapleura Tetraptera (Traditional African Food Spice):- Ude, Chinenyekalu. Repository.mouau.edu.ng: Retrieved Mar 04, 2025, from https://repository.mouau.edu.ng/work/view/comparative-study-of-the-antimicrobial-activities-of-locally-sold-herbal-mixture-and-the-crude-extract-of-tetrapleura-tetraptera-traditional-african-food-spice-ude-chinenyekalu-7-2
CHINENYEKALU, CHINENYEKALU. "Comparative Study Of The Antimicrobial Activities Of Locally Sold Herbal Mixture And The Crude Extract Of Tetrapleura Tetraptera (Traditional African Food Spice):- Ude, Chinenyekalu" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 03 Mar. 2025, https://repository.mouau.edu.ng/work/view/comparative-study-of-the-antimicrobial-activities-of-locally-sold-herbal-mixture-and-the-crude-extract-of-tetrapleura-tetraptera-traditional-african-food-spice-ude-chinenyekalu-7-2. Accessed 04 Mar. 2025.
CHINENYEKALU, CHINENYEKALU. "Comparative Study Of The Antimicrobial Activities Of Locally Sold Herbal Mixture And The Crude Extract Of Tetrapleura Tetraptera (Traditional African Food Spice):- Ude, Chinenyekalu". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 03 Mar. 2025. Web. 04 Mar. 2025. < https://repository.mouau.edu.ng/work/view/comparative-study-of-the-antimicrobial-activities-of-locally-sold-herbal-mixture-and-the-crude-extract-of-tetrapleura-tetraptera-traditional-african-food-spice-ude-chinenyekalu-7-2 >.
CHINENYEKALU, CHINENYEKALU. "Comparative Study Of The Antimicrobial Activities Of Locally Sold Herbal Mixture And The Crude Extract Of Tetrapleura Tetraptera (Traditional African Food Spice):- Ude, Chinenyekalu" Repository.mouau.edu.ng (2025). Accessed 04 Mar. 2025. https://repository.mouau.edu.ng/work/view/comparative-study-of-the-antimicrobial-activities-of-locally-sold-herbal-mixture-and-the-crude-extract-of-tetrapleura-tetraptera-traditional-african-food-spice-ude-chinenyekalu-7-2