ABSTRACT
Modified phylolherapeutic survey was adopted for
the present research work. Icacina trichantha Oliv was selected on the basis of
the claims of the indigenous medical practitioners that suggest (its use
against tuberculosis). The root was extracted, macerated and chromatographed to
ensure purity. Fractions were subjected to severe screening. The residue FEOI
macerated and concentrated to obtain, petroleum ether fractions obtained were
subjected to bio-assay techniques, antimicrobial screening assay (AMA) using
agar diffusion method and enzyme assay technique (EAT). Microbial inhibitions
in comparison with ciprofloxacin was carried out. Appreciable
Chemical inhibitory effect was also registered at all concentrations used. The
art tool of l3C nmr techniques spanning IH, l3C, 1H/IH COSY, II I/I3C COSY,
DEPT 45, 90 and 135 as well as FAB - mass; Data basing from A.C.DI elucidator,
further supported the proposed structure.
NDUKWE, C (2023). Chemical Investigation And Bio-Activity Of Icacina Trichantha Tuber As Anti-Tuberculosis Agent.. Repository.mouau.edu.ng: Retrieved Nov 23, 2024, from https://repository.mouau.edu.ng/work/view/chemical-investigation-and-bio-activity-of-icacina-trichantha-tuber-as-anti-tuberculosis-agent-7-2
CHINEMEREM, NDUKWE. "Chemical Investigation And Bio-Activity Of Icacina Trichantha Tuber As Anti-Tuberculosis Agent." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 10 Aug. 2023, https://repository.mouau.edu.ng/work/view/chemical-investigation-and-bio-activity-of-icacina-trichantha-tuber-as-anti-tuberculosis-agent-7-2. Accessed 23 Nov. 2024.
CHINEMEREM, NDUKWE. "Chemical Investigation And Bio-Activity Of Icacina Trichantha Tuber As Anti-Tuberculosis Agent.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 10 Aug. 2023. Web. 23 Nov. 2024. < https://repository.mouau.edu.ng/work/view/chemical-investigation-and-bio-activity-of-icacina-trichantha-tuber-as-anti-tuberculosis-agent-7-2 >.
CHINEMEREM, NDUKWE. "Chemical Investigation And Bio-Activity Of Icacina Trichantha Tuber As Anti-Tuberculosis Agent." Repository.mouau.edu.ng (2023). Accessed 23 Nov. 2024. https://repository.mouau.edu.ng/work/view/chemical-investigation-and-bio-activity-of-icacina-trichantha-tuber-as-anti-tuberculosis-agent-7-2