ABSTRACT

 This study was to access the antimicrobial and antioxidant properties of Telraplera tetraplera on some human pathogens. The antimicrobial activity of Tetraplera telraplera on some pathogens was investigated with different solvents (Ethanol, Methanol, Cold and Elot water) against lest organisms (Esherichia coli. Staphylococcus aureuas, Salmonella spp, Shigella, Aspergillus and Candida albican). The different extracts were prepared at different concentration (50mg/ml, 100 mg/ml, 150mg/ml and 200mg/ml). Amongst the different Telraplera telraplera extracts studies, ethanolic extract generated more phytochemical constituents than the methanol, cold water and hot water extracts. The study revealed that the ethanolic extract had more significant inhibitory effect than methanolic, cold water and hot water extracts. Salmonella spp. and Staphylococcus aureus, had the highest sensitivity (15mm. and 16mm) against the methanol and ethanol extract of Tetraplera tetraplera, followed by Aspergillus niger on the ethanolic extracts of Tetraplera tetraplera at 14mm. Ciprofloxacin and Chloramphenicol were used as control. The antioxidant potentials of Telraplera tetraplera plant extracts have been linked with their flavonoids contents may provide anti-inflammatory activity. Ethanolic extracts and methanolic extracts of Tetraplera tetraplera have broad-spectrum antimicrobial activity; hence can serve as natural therapeutic agent against some enteric pathogens.