Antioxidant component and in vitro antioxidant activity of methanol extract ofAlstonia boonei and Anthrocleista vogelli:- Abara, Erica C.
ABSTRACT
Oxidative
stress reflects an imbalance between the systemic manifestation of reactive
oxygen species and a biological system's ability to readily detoxify the
reactive intermediates or to repair the resulting damage. Oxidative stress
plays a major role in the development of chronic and degenerative diseases such
as cancer, arthritis, aging, autoimmune disorders, and cardiovascular and neuro
degenerative diseases. However in plants and animals, these free radicals are
deactivated by antioxidants. This study was designed to invstigate the presents
of antioxidant components (phenol, flavonoid, vitamin C, beta carotene and
lycopene) and in vitro antioxidant activities (DPPH,FRAP and Nitric oxide) of
methanol extracts of plants. A.bonnie and A.vogelli were used for this study.
The results showed that the methanol extracts ofA.vogelli and A.boimie possess
high content of antioxidant even at lower concentration especially phenol 1(312
± 5.10 and 282.2 ± 3.92mg/g) and flavonoid (1068.54 ± 25 and
414.58±2.30mg/100g) respectively. Antioxidant constituent of these extracts
enables them act as scavengers and convert the radicals to less reactive.
However, this finding suggest that since these methanol extracts otA.bommie and
A.vogelli possess high antioxidant components that can scavenge free radicals
and reactive oxygen species, thus, they can be used in pharmaceutical and food
industries in production ofdrugs and as a suppliment forthe treatment and
prevention ofdiseases such as cancer, asthma, aging,etc. caused by free
radicals.
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ABARA, A (2024). Antioxidant component and in vitro antioxidant activity of methanol extract ofAlstonia boonei and Anthrocleista vogelli:- Abara, Erica C. . Repository.mouau.edu.ng: Retrieved Nov 21, 2024, from https://repository.mouau.edu.ng/work/view/antioxidant-component-and-in-vitro-antioxidant-activity-of-methanol-extract-ofalstonia-boonei-and-anthrocleista-vogelli-abara-erica-c-7-2
ABARA, ABARA. "Antioxidant component and in vitro antioxidant activity of methanol extract ofAlstonia boonei and Anthrocleista vogelli:- Abara, Erica C. " Repository.mouau.edu.ng. Repository.mouau.edu.ng, 17 May. 2024, https://repository.mouau.edu.ng/work/view/antioxidant-component-and-in-vitro-antioxidant-activity-of-methanol-extract-ofalstonia-boonei-and-anthrocleista-vogelli-abara-erica-c-7-2. Accessed 21 Nov. 2024.
ABARA, ABARA. "Antioxidant component and in vitro antioxidant activity of methanol extract ofAlstonia boonei and Anthrocleista vogelli:- Abara, Erica C. ". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 17 May. 2024. Web. 21 Nov. 2024. < https://repository.mouau.edu.ng/work/view/antioxidant-component-and-in-vitro-antioxidant-activity-of-methanol-extract-ofalstonia-boonei-and-anthrocleista-vogelli-abara-erica-c-7-2 >.
ABARA, ABARA. "Antioxidant component and in vitro antioxidant activity of methanol extract ofAlstonia boonei and Anthrocleista vogelli:- Abara, Erica C. " Repository.mouau.edu.ng (2024). Accessed 21 Nov. 2024. https://repository.mouau.edu.ng/work/view/antioxidant-component-and-in-vitro-antioxidant-activity-of-methanol-extract-ofalstonia-boonei-and-anthrocleista-vogelli-abara-erica-c-7-2