Antifungal Properties Of Fluted Pumpkin (Telfairia Occidentalis) Pod And The Effect Of Its Extract On The Electrolyte Status Of Normal And Monosodium Glutamate — Intoxicated Rats
ABSTRACT
This study was carried out to determine the antifungal
properties of fluted pumpkin (Telfairia occidentalis) pod and the effect of its
ethanol extract on the electrolyte status of normal and monosodium glutamate
(MSG) — intoxicated rats. The antifungal activity of the pod was tested on the
following fungi pathogens; Aspergillus niger, Histoplasma encapsulatum,
Penicillun'z nolatum, Candida albicans, and Fusarium spp and compared with the
antifungal activity of a standard antifungal drug, ketoconazole using standard
methods. The effect of the ethanol extract of the pod was also determined using
standard methods. The electrolyte parameters were bicarbonate ion (HCO3 ),
potassium ion (K), sodium ion (Nat), and calcium ion (Ca2 ). The result of the
study on the antifungal properties of the pod indicated that at 2000mg/ml, the
pod could elicit significant activity against Aspergillus niger, Histoplasma
encapsulatuni, and Fusarium spp. The result of the study on the effect of the
ethanol extract of the Telfairia occidentalis pod on the electrolyte status of
normal and monosodium glutamate — intoxicated rats indicated that the extract
(which significantly decreased the concentration of bicarbonate ion) may reduce
the effect of monosodium glutamate — intoxication on the normal rats.
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MATTHEWS, E (2021). Antifungal Properties Of Fluted Pumpkin (Telfairia Occidentalis) Pod And The Effect Of Its Extract On The Electrolyte Status Of Normal And Monosodium Glutamate — Intoxicated Rats. Repository.mouau.edu.ng: Retrieved Nov 24, 2024, from https://repository.mouau.edu.ng/work/view/antifungal-properties-of-fluted-pumpkin-telfairia-occidentalis-pod-and-the-effect-of-its-extract-on-the-electrolyte-status-of-normal-and-monosodium-glutamate-intoxicated-rats-7-2
EZEKWESIRI, MATTHEWS. "Antifungal Properties Of Fluted Pumpkin (Telfairia Occidentalis) Pod And The Effect Of Its Extract On The Electrolyte Status Of Normal And Monosodium Glutamate — Intoxicated Rats" Repository.mouau.edu.ng. Repository.mouau.edu.ng, 14 Jul. 2021, https://repository.mouau.edu.ng/work/view/antifungal-properties-of-fluted-pumpkin-telfairia-occidentalis-pod-and-the-effect-of-its-extract-on-the-electrolyte-status-of-normal-and-monosodium-glutamate-intoxicated-rats-7-2. Accessed 24 Nov. 2024.
EZEKWESIRI, MATTHEWS. "Antifungal Properties Of Fluted Pumpkin (Telfairia Occidentalis) Pod And The Effect Of Its Extract On The Electrolyte Status Of Normal And Monosodium Glutamate — Intoxicated Rats". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 14 Jul. 2021. Web. 24 Nov. 2024. < https://repository.mouau.edu.ng/work/view/antifungal-properties-of-fluted-pumpkin-telfairia-occidentalis-pod-and-the-effect-of-its-extract-on-the-electrolyte-status-of-normal-and-monosodium-glutamate-intoxicated-rats-7-2 >.
EZEKWESIRI, MATTHEWS. "Antifungal Properties Of Fluted Pumpkin (Telfairia Occidentalis) Pod And The Effect Of Its Extract On The Electrolyte Status Of Normal And Monosodium Glutamate — Intoxicated Rats" Repository.mouau.edu.ng (2021). Accessed 24 Nov. 2024. https://repository.mouau.edu.ng/work/view/antifungal-properties-of-fluted-pumpkin-telfairia-occidentalis-pod-and-the-effect-of-its-extract-on-the-electrolyte-status-of-normal-and-monosodium-glutamate-intoxicated-rats-7-2