Antibacterial Activity Of Phyllantus Amarus And Euphorbia Hirta Linn On Selected Bacterial Pathogens.
ABSTRACT
The antibacterial activities of the leaves of
two Nigerian medicinal plants were evaluated on four bacterial species namely
Gram positive bacteria (Staphylococcus aureus and Enterococcus feacalis) and
Gram negative bacteria (Escherichia coli and Pseudomonas aeruginosa). Ethanolic
and aqueous extracts of the plants were studied. The in vitro antibacterial activity
was performed by agar disc diffusion and micro dilution broth assays. All the
extracts exhibited moderate to high level of broad spectrum antimicrobial
activities against these microorganisms. The antibacterial activity was
measured by the diameter zone of inhibition and minimum inhibitory
concentration (MIC). The diameter of zone of inhibition ranges from 9mm-20mm at
2000µg/ml of crude extracts per disc. The MIC values were between 15.63g/ml -
500g/ml. The activities of the crude extracts were comparable to the reference
antibiotics at standard concentration used per disc. Bactericidal and
bacteristatic effects varied with solvent type of extract and method of test
adopted. These findings are discussed in relation to the development of cheap
and acceptable herbal medicines as a means of disease control and sources of
novel molecules for combating the problem of microbial resistance to
conventional antibiotics.
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EBERE, E (2022). Antibacterial Activity Of Phyllantus Amarus And Euphorbia Hirta Linn On Selected Bacterial Pathogens.. Repository.mouau.edu.ng: Retrieved Apr 24, 2024, from https://repository.mouau.edu.ng/work/view/antibacterial-activity-of-phyllantus-amarus-and-euphorbia-hirta-linn-on-selected-bacterial-pathogens-7-2
EBERE, EBERE. "Antibacterial Activity Of Phyllantus Amarus And Euphorbia Hirta Linn On Selected Bacterial Pathogens." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 16 Dec. 2022, https://repository.mouau.edu.ng/work/view/antibacterial-activity-of-phyllantus-amarus-and-euphorbia-hirta-linn-on-selected-bacterial-pathogens-7-2. Accessed 24 Apr. 2024.
EBERE, EBERE. "Antibacterial Activity Of Phyllantus Amarus And Euphorbia Hirta Linn On Selected Bacterial Pathogens.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 16 Dec. 2022. Web. 24 Apr. 2024. < https://repository.mouau.edu.ng/work/view/antibacterial-activity-of-phyllantus-amarus-and-euphorbia-hirta-linn-on-selected-bacterial-pathogens-7-2 >.
EBERE, EBERE. "Antibacterial Activity Of Phyllantus Amarus And Euphorbia Hirta Linn On Selected Bacterial Pathogens." Repository.mouau.edu.ng (2022). Accessed 24 Apr. 2024. https://repository.mouau.edu.ng/work/view/antibacterial-activity-of-phyllantus-amarus-and-euphorbia-hirta-linn-on-selected-bacterial-pathogens-7-2