Anti-Inflammatory And Diuretic Activities Of Ethanolic Extracts Of Smilax Anceps Wild:- Ukoji, Nene A.
ABSTRACT
The present study investigated the
anti-inflammatory and diuretic activities of ethanolic extracts of leaves of
Smilax anceps. Twenty (20) adults rats were used for this study. They were
allowed to acclimatize to the environment for two weeks. The extracts were
administered to the rats at doses of 125, 250, 500, 1000 and 2000mg/kg body
weight. This was done intra-peritoneal during diuresis an orally during
anti-inflammation. For inflammation, aspirin was used as positive control and
normal saline for negative control. Four standard drugs (Furosemide,
Hydrochlorothiazide, Spironolactone and Acetazolamide) were employed for
diuretic activity and normal saline as control. The extracts produced a
significant effect on the rats as compared to Aspirin during inflammation. The
diuretic effects were evaluated by measuring urine volume. The plant extracts
produced a significant effect on urine volume. Higher volumes were observed at
250 and 500mg/kg (1.10±0.14 and 0.80±0.57) respectively. The results obtained
showed that the ethanolic leaf extracts of Smilax anceps has potential
anti-inflammatory and diuretic properties. It could be suggested that it can be
used in the treatment of inflammation and diuretic problems.
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NENE, A (2024). Anti-Inflammatory And Diuretic Activities Of Ethanolic Extracts Of Smilax Anceps Wild:- Ukoji, Nene A.. Repository.mouau.edu.ng: Retrieved Nov 27, 2024, from https://repository.mouau.edu.ng/work/view/anti-inflammatory-and-diuretic-activities-of-ethanolic-extracts-of-smilax-anceps-wild-ukoji-nene-a-7-2
ACHI, NENE. "Anti-Inflammatory And Diuretic Activities Of Ethanolic Extracts Of Smilax Anceps Wild:- Ukoji, Nene A." Repository.mouau.edu.ng. Repository.mouau.edu.ng, 26 Feb. 2024, https://repository.mouau.edu.ng/work/view/anti-inflammatory-and-diuretic-activities-of-ethanolic-extracts-of-smilax-anceps-wild-ukoji-nene-a-7-2. Accessed 27 Nov. 2024.
ACHI, NENE. "Anti-Inflammatory And Diuretic Activities Of Ethanolic Extracts Of Smilax Anceps Wild:- Ukoji, Nene A.". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 26 Feb. 2024. Web. 27 Nov. 2024. < https://repository.mouau.edu.ng/work/view/anti-inflammatory-and-diuretic-activities-of-ethanolic-extracts-of-smilax-anceps-wild-ukoji-nene-a-7-2 >.
ACHI, NENE. "Anti-Inflammatory And Diuretic Activities Of Ethanolic Extracts Of Smilax Anceps Wild:- Ukoji, Nene A." Repository.mouau.edu.ng (2024). Accessed 27 Nov. 2024. https://repository.mouau.edu.ng/work/view/anti-inflammatory-and-diuretic-activities-of-ethanolic-extracts-of-smilax-anceps-wild-ukoji-nene-a-7-2