ABSTRACT 

Antibiotics are chemical substances that have the ability to inhibit or destroy microorganisms. Soil that was contaminated with abattoir effluents was investigated using general medium (nutrient agar) and selective media (glycerol nutrient agar and glycerol yeast agar). In the enumeration of total viable count, the result showed high bacteria counts, which ranged from 9.5 x 108 to 2.05 x 109 cfu/g soil. The soils were screened for antibiotic producing bacteria by agar sensitivity test. The bacterial isolated were identified by their colony features, microscopic structures, biochemical tests and by molecular characteristics. The bacterial isolates include Staphylococcus aureus, Bacillus subtilis, B. cereus, B.coagulans, Escherichia coli, Pseudomonas spp, Streptomyces globosus, S. hygroscopicus, S. oriantalis, and Micrococus spp. Among all the isolates, Bacillus subtilis , B. cereus, B.coagulans, Streptomyces globosus, S. hygroscopicus, and S. oriatalis exhibited antibiotics production by evidence of zone of inhibition round their colonies. The statistical analyses done on the antibacterial activity of the isolates revealed significant difference (P˂0.05) between the antibacterial agents produced by organisms and the chloramphenicol which is the standard. This study revealed that abattoir soils have the growth factors that can enhance the proliferation of antibiotic producing bacteria, which have the potency of secreting antibiotics that can be used in the now and in the future for the control of  microbial growth.