Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacin-Ulcerated Rats:-Nkwocha, Doreen E.

NKWOCHA DOREEN EBERE | 64 pages (12516 words) | Projects

ABSTRACT

Plants have been the basis for trado-medical treatments through much of human history and such traditional medicine is still widely in use today such as the leaves of M. paradisiaca. The objectives of this work were to examine the phytochemical constituents, acute toxicity and lethality and effect of the methanol extract of the leaves of M. paradisiaca on red blood cell count of indomethacin-ulcerated rats. The preliminary phytochemical screening revealed that the plant leaves contained alkaloids, flavonoids, tannins, saponins, carbohydrates, reducing sugars, proteins, steroids, terpenoids and fats and oil but resins, glycosides and acidic compounds were not detected. The extract was found to be safe at a dose as high as 5000 mg/kg body weight (b.w). The extract at the tested doses (100, 200 and 400 mg/kgb.w) significantly (p < 0.05) and dose-dependently increased the red blood cell count ofthe rats in the test groups when compared to the value obtained for the rats in the ulcer-untreated group. The effect ofthe 400 mg/kg b.w of the extract was similar to that ofthe standard anti-ulcer drug, famotidine at the dose of 50 mg/kg b.w. The results indicate that the methanol extract ofthe leaves of M. paradisiaca contains some pharmacological active principles which may raise the red blood cell count in ulcerated rats. 

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APA

NKWOCHA, E (2024). Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacin-Ulcerated Rats:-Nkwocha, Doreen E. . Repository.mouau.edu.ng: Retrieved Apr 23, 2024, from https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacin-ulcerated-rats-nkwocha-doreen-e-7-2

MLA 8th

EBERE, NKWOCHA. "Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacin-Ulcerated Rats:-Nkwocha, Doreen E. " Repository.mouau.edu.ng. Repository.mouau.edu.ng, 20 Feb. 2024, https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacin-ulcerated-rats-nkwocha-doreen-e-7-2. Accessed 23 Apr. 2024.

MLA7

EBERE, NKWOCHA. "Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacin-Ulcerated Rats:-Nkwocha, Doreen E. ". Repository.mouau.edu.ng, Repository.mouau.edu.ng, 20 Feb. 2024. Web. 23 Apr. 2024. < https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacin-ulcerated-rats-nkwocha-doreen-e-7-2 >.

Chicago

EBERE, NKWOCHA. "Effect Of The Methanol Extract Of The Leaves Of Musa Paradisiaca On The Red Blood Cell (Rbc) Count Of Indomethacin-Ulcerated Rats:-Nkwocha, Doreen E. " Repository.mouau.edu.ng (2024). Accessed 23 Apr. 2024. https://repository.mouau.edu.ng/work/view/effect-of-the-methanol-extract-of-the-leaves-of-musa-paradisiaca-on-the-red-blood-cell-rbc-count-of-indomethacin-ulcerated-rats-nkwocha-doreen-e-7-2

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