ABSTRACT

The effect of some antibacterial soaps; Delta, Dettol, Duduosun, Tura and Zee were evaluated on Escherichia coli and Staphylococcus aureus isolates using disc diffusion method. Analysis of the antibacterial activities of the soaps were carried out using different concentrations; 50mg/ml, I 00mg/ml, 200mg/ml, 300mg/ml, 400mg/ml and 500mg/ml. The highest diameter of inhibition for both organisms were recorded with 500mg/ml concentration, with E. coli showing zone of inhibition of 14.33mm and S. aureus, 16.67mm with Delta soap. E. coli showed 12.67mm and S, aureus showed 13.33mm zones of inhibition with Dettol soap. With Dudu osun, E. coli showed zone of inhibition of 15.67mm and S. aureus, 18.00mm. With Tura, E. coli showed 12.00mm and S. aureus, 1 2.00mm zones of inhibition while with Zee, E. coli showed I 6.67mm and S. aureus. 20.00mm zones of inhibition. The lowest diameter of inhibition for both organisms was recorded with 50mg/ml concentration, where the test organisms showed no inhibition with Delta, Dettol and Tura. With Dudu osun and Zee, E. coli showed 6.33mm and 8.33mm respectively, while S. aureus showed 7.33mm and 9.67mm zones of inhibition respectively. For £. coli, the lowest MIC of 62.5mg/ml was recorded by Zee while the highest MIC of 500mg/ml was recorded by Tura and Dettol. Zee produced the lowest MIC of 62.5mg/ml on S, aureus while the highest MIC of 500mg/ml was produced by Tura. There was no significant difference (P>0.05) in the activities of Zee and Dudu osun soaps on the test organisms, no significant difference (P>0.05) in the activities of Delta and Dettol soaps on the test organisms, but there was significant difference (P< 0.05) between all the soaps and Tura. The antibacterial activities of these soaps on the test organisms are in decreasing order as follows; Zee, Dudu osun, Delta, Dettol and Tura. The result obtained so far in this study showed that Zee and Dudu osun soaps have a high potential for use in the treatment of skin diseases and skin disinfections